Contrôle des évolutions d'un système d'information pour la recherche clinique

In order to face evolutions of software systems, model-driven engineering (MDE) uses model transformations for software development. This paper focuses on issues that are essential in the context of information systems that process data from clinical trials. Indeed, such software systems should adapt to recurrent evolutions of their contexts. This way, by defining model structures and model components behaviours, definition of extension points allows to describe model evolutions, and thus makes it possible to manage them. In this paper we propose to define a framework for applied models transformations in order to master evolution requirements of an information retrieval system. MOTS-CLÉS : ingénierie dirigée par les modèles, évolution, système d’information scientifique.